Restarting Oral Anticoagulation After Intracranial Hemorrhage

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Restarting oral anticoagulation after intracranial hemorrhage.

To the Editor: In their recent article, Eckman and colleagues highlight a difficult clinical decision: whether it is safe to restart anticoagulation for atrial fibrillation after intracerebral hemorrhage, and they cite the lack of published data addressing the issue.1 We agree that decisions must be made based on the relative risks versus benefits in individual patients, which will vary dependi...

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Restarting Anticoagulant Therapy After Intracranial Hemorrhage

Atrial fibrillation increases the risk of stroke 3to 5-fold and is implicated in about 15% of all strokes every year. Anticoagulation therapy has been proven to be efficacious in reducing incident stroke and systemic embolism in patients with atrial fibrillation and mechanical heart valves. However, the benefits of anticoagulation must be carefully weighed against the increased risk of intracra...

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Oral anticoagulation in patients after cerebral ischemia of arterial origin and risk of intracranial hemorrhage.

BACKGROUND AND PURPOSE In the recently published Warfarin Aspirin Recurrent Stroke Study (WARSS), a low-intensity anticoagulation regimen was used because of safety concerns. Such concerns are corroborated by the results of the Stroke Prevention in Reversible Ischemia Trial (SPIRIT), which was stopped early because of a high incidence of intracranial hemorrhage with a target international norma...

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Resumption of oral anticoagulation after warfarin-associated intracerebral hemorrhage: yes.

A hematology/thrombosis consultation for a patient admitted with warfarin-associated intracerebral hemorrhage (ICH) should take into account the indication for anticoagulation, the treatment history with warfarin, any possible precipitating risk factors for the hemorrhage, the location of the hematoma, and the condition of the patient. Finally, the balance between the risk for ischemic stroke w...

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Intracranial hemorrhage in patients with atrial fibrillation receiving anticoagulation therapy.

We investigated the frequency and characteristics of intracranial hemorrhage (ICH), the factors associated with the risk of ICH, and outcomes post-ICH overall and by randomized treatment. We identified patients with ICH from the overall trial population enrolled in the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation trial who received ≥1 dose of the study...

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ژورنال

عنوان ژورنال: Stroke

سال: 2004

ISSN: 0039-2499,1524-4628

DOI: 10.1161/01.str.0000107226.46616.86